The term most destroying refers to something that causes a great deal of harm or damage. Antonyms for this phrase can be words that imply preservation, growth or improvement. To describe something that helps to preserve, "protective", "conservative" and "constructive" can serve as antonyms. Words such as "healing", "rebuilding" and "renewing" suggest growth, health and improvement, respectively. "Beneficial", "constructive" and "vital" are other examples of antonyms for most destroying. Using these words helps to convey a positive sentiment and might be useful when writing about topics such as environmental conservation, healthcare or economic development.